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Can a dog have OSA?

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Can a dog have OSA?

Postby PhotoFred » Mon Feb 06, 2006 2:47 am

Can a dog have OSA?
I have an English bulldog and he is very cute by the way. I have been told that they have a small airway passage (it is dangerous to put them under for surgery etc) and because of the way there face is smashed (not by me) and the small airway they have a hard time breathing. My dog can snoore like you would not belive, he gave me a run for money. Sometimes I notice he will be snoreing away and out of no where he will jump and wake up, look at me with those oh so cute droopy eyes and go back to sleep. Is it possible that he just had an event? I put this in the late night section because I know it sounds crazy. Any thoughts?
PhotoFred
 
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Joined: Wed Dec 21, 2005 11:51 pm

Yes. I believe it is well known in the English bulldog.

Postby RK » Sun Sep 30, 2007 2:27 am

think it might be more common in brachycephalic dogs (e.g., Boston terrier, Pekingese, boxer, bulldog, shih tzu) than you might think. My sister has a pug mix and he sometimes snores lightly when he sleeps although he does not have a flat face. He does have a thick neck and short snout. I've wondered if he has UARS and whether somebody has developed a C-PUP for dogs.

Here's an article from Medline:

Pharyngeal myopathy of loaded upper airway in dogs with sleep apnea.Petrof BJ, Pack AI, Kelly AM, Eby J, Hendricks JC.
Department of Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104.

Recent work indicates that upper airway dilator muscles of individuals with obstructive sleep apnea syndrome (OSAS) demonstrate an increased level of activity during wakefulness compared with normal subjects. In addition, massive bursts of pharyngeal dilator activity are associated with the termination of upper airway occlusive events during sleep. This complex pattern of altered pharyngeal dilator activation is also observed in the English bulldog, an animal model of OSAS. In the present study, it was hypothesized that such alterations in activity level might lead to changes in the structure of pharyngeal muscles in the bulldog. Full-thickness biopsies were obtained from two pharyngeal dilator muscles, the sternohyoid (SH) and geniohyoid, as well as a limb muscle, the anterior tibialis, in bulldogs (n = 5) and control dogs (n = 7). Immunohistochemical analysis of myosin heavy chain expression revealed an increased contribution of fast type II myosin heavy-chain fibers to SH in bulldogs. The bulldog SH also demonstrated increased connective tissue content compared with control dogs, consistent with the presence of fibrosis. Both pharyngeal dilators in the bulldog exhibited an elevated proportion of morphologically abnormal fibers indicative of ongoing or prior injury. No differences in any of the above parameters were seen between bulldogs and control dogs in the anterior tibialis limb muscle. We conclude that the chronic load and altered pattern of usage imposed on the upper airway dilators in OSAS lead to myopathic changes that may ultimately impair the ability of these muscles to maintain pharyngeal patency.


IPMID: 8045855 [PubMed - indexed for MEDLINE]
RK
 
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