a.b.luisi,d.m.d. wrote:Patients prefer OA's over CPAP in a ratio of 10-20 to 1 and the compliance rate is better.
Where on earth did you get that figure from ?
Daniel.
I will cite one study. I have others: From Sleep Review, Medical World Communications, "Oral Appliance Therapy for SDB" Jeffrey P. Pancer,DDS July/August 2003(Note: Jeffrey Pancer is a Diplomate of the AADSM and past president of the American Academy of Dental Sleep Medicine, device tested was TAP3.) "Patients in our study prefer oral appliances to CPAP 20:1; 99 patients preferred oral appliances given the choice,with four patients who had good results with an oral appliance still preferring CPAP and using oral appliances only for travelling."[/quote]
The study that you quote is dated 2003....a little dated. In fact I have been unable to find a link to it on pubmed or similar databases. It is always helpful to quote relative URLs so that members can see the full text/paramaters of the study or abstract.
More updated studies are as follows:
http://www.ncbi.nlm.nih.gov/pubmed/21636666Efficacy of an adjustable oral appliance and comparison with continuous positive airway pressure for the treatment of obstructive sleep apnea syndrome.
Holley AB, Lettieri CJ, Shah AA. (2011)
Source
Department of Pulmonary/Sleep and Critical Care Medicine, Walter Reed National Military Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889, USA.
aholley9@gmail.comAbstract
BACKGROUND:
We sought to establish the efficacy of an adjustable oral appliance (aOA) in the largest patient population studied to date, to our knowledge, and to provide a comparison with continuous positive airway pressure (CPAP).
METHODS:
We conducted a retrospective analysis of patients using an aOA. Results of overnight polysomnography with aOA titration were evaluated and compared with CPAP. Predictors of a successful aOA titration were determined using a multivariate logistic regression model.
RESULTS:
A total of 497 patients were given an aOA during the specified time period. The aOA reduced the mean apnea-hypopnea index (AHI) to 8.4 ± 11.4, and 70.3%, 47.6%, and 41.4% of patients with mild, moderate, and severe disease achieved an AHI < 5, respectively. Patients using an aOA decreased their mean Epworth Sleepiness Score by 2.71 (95% CI, 2.3-3.2; P < .001) at follow-up. CPAP improved the AHI by -3.43 (95% CI, 1.88-4.99; P < .001) when compared with an aOA, but when adjusted for severity of disease, this difference only reached significance for patients with severe disease (-5.88 [95% CI, -8.95 to -2.82; P < .001]). However, 70.1% of all patients achieved an AHI < 5 using CPAP compared with 51.6% for the aOA (P < .001). On multivariate analysis, baseline AHI was a significant predictor of achieving an AHI < 5 on aOA titration, and age showed a trend toward significance.
CONCLUSIONS:
In comparison with past reports, more patients in our study achieved an AHI < 5 using an aOA.
The aOA is comparable to CPAP for patients with mild disease, whereas CPAP is superior for patients with moderate to severe disease. A lower AHI was the only predictor of a successful aOA titration.
http://www.ncbi.nlm.nih.gov/pubmed/21239397Eur J Orthod. 2011 Jun;33(3):318-24. Epub 2011 Jan 13.
A systematic review of the efficacy of oral appliance design in the management of obstructive sleep apnoea.
Ahrens A, McGrath C, Hägg U.
Source
Discipline of Dental Public Health, Faculty of Dentistry, The University of Hong Kong, SAR China.
Abstract
Oral appliances (OAs) are increasingly advocated as a treatment option for obstructive sleep apnoea (OSA). However, it is unclear how their different design features influence treatment efficacy. The aim of this research was to systematically review the evidence on the efficacy of different OAs on polysomnographic indices of OSA. A MeSH and text word search were developed for Medline, Embase, Cinahl, and the Cochrane library. The initial search identified 1475 references, of which 116 related to studies comparing OAs with control appliances. Among those, 14 were randomized controlled trials (RCTs), which formed the basis of this review. The type of OA investigated in these trials was mandibular advancement devices (MADs), which were compared with either inactive appliances (six studies) or other types of MADs with different design features. Compared with inactive appliances, all MADs improved polysomnographic indices, suggesting that mandibular advancement is a crucial design feature of OA therapy for OSA. The evidence shows that there is no one MAD design that most effectively improves polysomnographic indices, but that efficacy depends on a number of factors including severity of OSA, materials and method of fabrication, type of MAD (monobloc/twin block), and the degree of protrusion (sagittal and vertical).
These findings highlight the absence of a universal definition of treatment success. Future trials of MAD designs need to be assessed according to agreed success criteria in order to guide clinical practice as to which design of OAs may be the most effective in the treatment of OSA.http://www.ncbi.nlm.nih.gov/pubmed/19852636Angle Orthod. 2010 Jan;80(1):30-6.
Five years of sleep apnea treatment with a mandibular advancement device. Side effects and technical complications.
Martínez-Gomis J, Willaert E, Nogues L, Pascual M, Somoza M, Monasterio C.
Source
Department of Prosthodontics, Faculty of Dentistry, University of Barcelona, Campus de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
jmartinezgomis@ub.eduAbstract
OBJECTIVE:
To determine the variation in prevalence of temporomandibular disorders (TMD), other side effects, and technical complications during 5 years of sleep apnea treatment with a mandibular advancement device.
MATERIALS AND METHODS:
Forty patients diagnosed with obstructive sleep apnea received an adjustable appliance at 70% of the maximum protrusion. The protrusion was then progressively increased. TMD (diagnosed according to the Research Diagnostic Criteria for TMD), overjet, overbite, occlusal contacts, subjective side effects, and technical complications were recorded before and a mean of 14, 21, and 58 months after treatment and analyzed by the Wilcoxon test (P < .05).
RESULTS:
Fifteen patients still used the oral appliance at the 5-year follow-up, and no significant variation in TMD prevalence was observed. Subjective side effects were common, and a significant reduction was found in overjet, overbite, and in the number of occlusal contacts.
Furthermore, the patients made a mean of 2.5 unscheduled dental visits per year and a mean of 0.8 appliance repairs/relines per year by a dental technician. The most frequent unscheduled visits were needed during the first year and were a result of acrylic breakage on the lateral telescopic attachment, poor retention, and other adjustments to improve comfort.
CONCLUSIONS:
Five-year oral appliance treatment does not affect TMD prevalence but is
associated with permanent occlusal changes in most sleep apnea patients during the first 2 years. Patients seek several unscheduled visits, mainly because of technical complications.
These studies are all within the past two years. Some of the conclusions are at variance with some of your comments.
I have already mentioned on a number of occassions that Oral Appliances do have a place in treating OSA, primarily in the mild/moderate area....but stating that patients prefer Oral Appliances to CPAP at a rate of 20:1....really !!!
Within the paramaters of the study quoted..maybe...but what were the paramaters ? BUT your figures quoted indicate that from all OSA sufferers there is a 20:1 ratio in favour of Oral Appliances.........if this is the case, why is dental treatment for OSA still in its infancy, with very few (relative to respiratory/ENT sleep specialists) practitioners.
Daniel.
The untreated Sleep Apnoea sufferer died quietly in his sleep..
Unlike his three passengers who died screaming !
Stress
The confusion created when one’s mind overrides the body's desire to kick the s#!@ out of some a** hole who richly deserves it